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DNA Vaccine for HIV Moves Forward with Tier-2 Neutralization in Mice

Unlike many other retroviruses, HIV is an enveloped virus, enabling scientists to target the envelope for the induction of neutralizing antibodies in vaccine development efforts. Protein immunizations that induce autologous neutralizing antibodies (nAbs) against difficult to neutralize HIV strains (tier-2) require the stabilization of the HIV envelope into native-like trimer (NLT) conformations. A new study has encoded the HIV NLT into DNA and used this to successfully induce tier-2 nAbs in mice...
Daniel Kulp David Weiner Us Centers For Disease Vaccine Immunotherapy Center Wistar Institute Nature Communications On

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Health News | Scientists Develop Immunogen That Produces Tier-2 Antibodies Against HIV

Get latest articles and stories on Health at LatestLY. Nearly four decades after its discovery, HIV has killed 36.3 million people, with no vaccine in sight. And many people are still not open in talking about it due to the stigma attached to it. However, a new study by researchers at The Wistar Institute has taken a promising step in the direction of developing an HIV vaccine. Health News | Scientists Develop Immunogen That Produces Tier-2 Antibodies Against HIV.
United States Davidb Weiner Daniel Kulp Nature Communications Vaccine Immunotherapy Center Wistar Institute

Wistar researchers takes a promising step in the direction of developing HIV vaccine

Nearly four decades after its discovery, HIV has killed 36.3 million people, with no vaccine in sight. However, a new study by researchers at The Wistar Institute, an international biomedical research leader in cancer, immunology, infectious disease, and vaccine development, takes a promising step in the direction of developing an HIV vaccine.
Davidb Weiner Daniel Kulp Emily Henderson Nature Communications Vaccine Immunotherapy Center Wistar Institute

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