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Circulating cell-free mitochondrial DNA could be useful biomarkers for aging and inflammation

In an eight-year study of more than 600 community-dwelling older adults, Johns Hopkins Medicine researchers say they have further linked levels of cell-free DNA (DNA fragments resulting from cell death) circulating in the blood to chronic inflammation and frailty.
Lolita Nidadavolu Francine Grodstein Yuqiong Wu Alden Gross Johns Hopkins Peter Abadir

Cell-free DNA circulating in the blood may signal early signs of dementia and frailty

In a long-term prospective study of more than 600 older participants, Johns Hopkins Medicine researchers say they have evidence that higher levels of cell-free DNA circulating in the blood may signal increased risk of chronic inflammation associated with early signs of frailty and dementia.
United States Peter Abadir Danielle Feger Lolita Nidadavolu Jeremy Walston Francine Grodstein

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