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New method helps map the specialized diversity and spatial location of cells within a tissue or tumor

New method helps map the specialized diversity and spatial location of cells within a tissue or tumor Not all cancer cells within a tumor are created equal; nor do all immune cells (or all liver or brain cells) in your body have the same job. Much of their function depends on their location. Now, researchers at Gladstone Institutes, UC San Francisco (UCSF), and UC Berkeley have developed a more efficient method than ever before to simultaneously map the specialized diversity and spatial locatio...
Eric Chow Youjin Lee Derek Bogdanoff Emily Henderson Alex Marson Institute Of Genomic Immunology

XYZeq: A better map of cell diversity

ย E-Mail SAN FRANCISCO, CA--April 21, 2021--Not all cancer cells within a tumor are created equal; nor do all immune cells (or all liver or brain cells) in your body have the same job. Much of their function depends on their location. Now, researchers at Gladstone Institutes, UC San Francisco (UCSF), and UC Berkeley have developed a more efficient method than ever before to simultaneously map the specialized diversity and spatial location of individual cells within a tissue or a tumor. The tech...
United States San Francisco Codyt Mowery Joshua Cantlon Theodorel Roth Youjin Lee

A genetic shortcut to help visualize proteins at work

ย E-Mail IMAGE:ย A team led by Nevan Krogan at Gladstone and UCSF has demonstrated that a large-scale and systematic genetic approach can indeed yield reliable and detailed information on the structure of... view moreย  Credit: QBI, UCSF SAN FRANCISCO, CA--December 10, 2020--One of biologists most vexing tasks is figuring out how proteins, the molecules that carry the brunt of a cells work, do their job. Each protein has a variety of knobs, folds, and clefts on its surface that dictate w...
Junbiao Dai Jamess Fraser David Mavor Jamese Haber John Morris Briand Strahl

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