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January 21, 2024
This article revises criteria to identify sepsis in children after an exhaustive process that involved, surveying clinicians, reviewing health record databases,
October 25, 2023
Two randomized clinical trials were harmonized to compare the effect of vitamin C vs control on outcomes in hospitalized patients with COVID-19 who were critica
September 1, 2023
A program designed to ensure fairness and that people living in the most disadvantaged U.S. neighborhoods would be offered a scarce, potentially life-saving medication proved feasible in a large health system.
June 2, 2023
This open label clinical trial compares the effects of dexamethasone vs usual care on the number of days alive and free of mechanical ventilation at day 28 amon
April 28, 2023
This meta-analysis pools data from 7 randomized trials to estimate the association between administration of corticosteroids vs usual care or placebo and all-ca
April 11, 2023
This randomized clinical trial examines the effect of initiation of a renin-angiotensin system inhibitor (ACE inhibitor or an angiotensin receptor blocker) on t
December 21, 2022
This secondary analysis of an ongoing adaptive platform trial examines the effect of multiple interventions for critically ill adults with COVID-19 on longer-te
March 22, 2022
This randomized clinical trial assesses the effect of treatment with an antiplatelet agent vs no antiplatelet therapy on days alive and free of intensive care u
February 27, 2022
This single-center case series describes the demographics, symptoms, laboratory and imaging findings, treatment, and clinical course of 138 patients hospitalize
December 23, 2021
This Viewpoint discusses the challenges to detecting sepsis in patients early in the disease course and suggests ways to improve the diagnosis and outcomes of s