Diffuse Scleroderma News Today

Area under the curve for routine biomarkers distinguished infected and noninfected adults with inflammatory diseases.

In patients with SSc, the presence of inflammatory arthritis is significantly associated with diffuse disease, musculoskeletal manifestations, myositis, and sicca.

Scleroderma is a complex autoimmune disorder that affects connective tissues, characterized by skin tightening and internal organ fibrosis. You can manage its symptoms by staying warm or by using saline soaks or warm water.

Weakened bioavailability of mycophenolate mofetil could require adjustments in treatment.

Patients with idiopathic pulmonary fibrosis who required dose reductions had similar all-cause mortality and death rates vs patients on the full dose.

Compared with men, women receive a diagnosis of rheumatic disease much later and are treated more poorly, research suggests.

Patients with both systemic sclerosis (SSc) and systemic lupus erythematosus (SLE) showed a distinct clinical phenotype from those with SSc alone, but mortality was similar.

Patients with systemic sclerosis who have both interstitial lung disease and pulmonary hypertension have worse survival than those without both conditions, based on data from more than 3000 individuals.

If validated as a biomarker, anti-gephyrin autoantibodies could help identify patients at higher risk for GI symptoms like constipation.

Nearly half of these patients had interstitial lung disease and had similar rates of scleroderma renal crisis, compared with the other disease subtypes.