Patients with both systemic sclerosis (SSc) and systemic lupus erythematosus (SLE) showed a distinct clinical phenotype from those with SSc alone, but mortality was similar.
Patients with systemic sclerosis who have both interstitial lung disease and pulmonary hypertension have worse survival than those without both conditions, based on data from more than 3000 individuals.
Nearly half of these patients had interstitial lung disease and had similar rates of scleroderma renal crisis, compared with the other disease subtypes.