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November 30, 2022
Scientists at the Francis Crick Institute, in collaboration with Artios, have identified how an enzyme involved in DNA repair (POLQ), becomes vital to the survival of certain cancers, if the cancer cells lose the ability to use a more common method of DNA repair.
November 1, 2022
In the tough war against glioblastoma, scientists are taking a cue from viruses on how to make the aggressive cancer more vulnerable to treatment.
October 30, 2022
Around this time of year, my biology for science majors course begins to cover the core of the inner workings of life on Earth. How do cells get energy, how
October 28, 2022
Genetic mutations kick start cancers. Some mutations shuffle the genetic code, others come from the deletion of key genes.
October 21, 2022
In this study, researchers systematically demonstrated the transcriptional and posttranscriptional levels of ORCs as well as their prognostic value in LUAD.
October 5, 2022
The molecular mechanisms that support life depend on the fate of small populations of molecules. The functions of biomolecules, however, are traditionally characterised through bulk-phase biochemical methods that only report on ensemble averages. Such methods are not sensitive to population heterogeneity or short-lived reaction intermediates. Single-molecule methods that allow for the direct observation of individual molecules have significantly advanced our understanding of biology in the past ...
September 21, 2022
Researchers have uncovered a novel pathway that explains how cancer cells become resistant to chemotherapies, which in turn offers a potential solution for preventing chemo-resistance.
August 23, 2022
Scientists at the UNC School of Medicine have made the surprising discovery that a molecule called EdU, which is commonly used in laboratory experiments to label DNA, is in fact recognized by human cells as DNA damage, triggering a runaway process of DNA repair that is eventually fatal to affected cells, including cancer cells.
August 10, 2022
Knowing the structure of a complex biological system isn't nearly enough to understand how it works. It helps to know how the system moves.
August 8, 2022
A recent study reviewed the current progress on 3D interactions between host and viral genomes.