At the heart of nanotechnology lies the nanoparticle, with dimensions on the nanoscale. Learn more about the use of particle analysis in nanoscience on AZoNano.
To ensure the stability and usability of injectable biopharmaceutical products, protein aggregation and active principle ingredients are of the utmost concern.
Wet bead milling is used to produce nanoparticles at industrial scales. Continuous monitoring of particle size during comminution would allow real-time end-point determination and critical quality attribute monitoring, reducing operational risk and increasing insight into particle breakage kinetics.