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Novel oral nano-in-micro system provides efficient curcumin delivery to alleviate ulcerative colitis

A new study showed that the newly designed oral nano-in-micro hydrogel delivery platform could be efficiently used to deliver curcumin for the treatment of Ulcerative Colitis.
Alona Siniehina Shutterstock Drug Administration Nuclear Factor Kappa Mitogen Activated Protein Kinase Peroxisome Proliferator Activated Receptor Nuclear Factor Kappa B

Synthetic molecule Pep19 helps regulate and balance key metabolic functions, study shows

A study conducted at the University of São Paulo in Brazil shows that the synthetic molecule Pep19 acts on the endocannabinoid system, which helps regulate and balance key metabolic functions, such as appetite, fat breakdown (lipolysis), and energy release.
Emer Suavinho Ferro Emily Henderson Biomedical Center International Journal Of Molecular Sciences Paulo Biomedical Sciences Institute Pharmacology Department Of The University

Mosaic-8 RBD-nanoparticles show promise against current and future SARS-CoV-2 variants

A recent study posted to the bioRxiv* preprint server supports using mosaic sarbecovirus receptor-binding domain (RBD)-nanoparticles to discover therapeutic pan-variant and pan-sarbecovirus monoclonal antibodies (mAbs) and to induce mAbs by vaccination.
Spytagged Rbds California Institute Of Technology Beckman Research Institute Of City Hope Stanford University Beckman Research Institute California Institute

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