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Overlap in pro-inflammatory genes and pathways between COVID-19 and MIS-C

In a recent study posted to the medRxiv* pre-print server, researchers in the United States characterized differential host immune responses in acute coronavirus disease 2019 (COVID-19) and multisystem inflammatory syndrome in children (MIS-C) to inform future development of novel biomarkers for both diseases.
United States Image Credit Tabula Sapiens Coronavirus Disease Covid 19 Ell Death Immune Response

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Study uncovers cryptic vulnerabilities in RET oncogene that could aid in anti-cancer drug design

RET is a receptor protein with tyrosine kinase activity that can transfer a phosphate group from ATP to other molecules modifying their shape and function in signaling pathways that are essential to organogenesis and tissue maintenance.
Ivan Plaza Menacho Emily Henderson Cancer Group Spanish National Cancer Research Centre Experimental Therapeutics Programme Protein Phosphorylation

Analyzing biophysical restrictions of SARS-CoV-2 N-terminal domain

In a recent article posted to the bioRxiv* preprint server, researchers at the University of Illinois at Urbana-Champaign, Scripps Research Institute, and Case Western Reserve University evaluated the biophysical limitations of the spike (S) N-terminal domain (NTD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
Scripps Research Institute Case Western Reserve University University Of Illinois At Urbana Champaign Image Credit Rosetta App Coronavirus Disease Covid 19

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