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Core body temperature increases host resistance to influenza virus and SARS-CoV-2 infection

A recent article posted to the Research Square* preprint server demonstrated that high body temperature elevates gut microbiota-reliant host resistance against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza A viral infection.
Research Square Takedag Protein Coupled Coronavirus Disease Covid 19 Ars Cov 2 Covid 19 Mass Spectrometry

Research suggests two protein coding genes can predict severe COVID-19

In a recent study posted to the medRxiv* pre-print server, researchers demonstrated that two genes, GTPase, IMAP Family Member 7 (GIMAP7), and sphingosine-1-phosphate receptor 2 (S1PR2), have the potential to predict severe coronavirus disease 2019 (COVID-19) with ~90% accuracy.
Transcriptomics Meta Marcin Janiec Severe Infection Automated Reproducible Gini Impurity Coronavirus Disease Covid 19

Synthetic IL-9 receptor allows T cells to fight cancer without the need for chemo or radiation

Before a patient can undergo T cell therapy designed to target cancerous tumors, the patient's entire immune system must be destroyed with chemotherapy or radiation. The toxic side effects are well known, including nausea, extreme fatigue and hair loss.
Antoni Ribas Mikko Siurala Christopher Garcia Anusha Kalbasi Emily Henderson Garcia Lab At Stanford

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Oral administration of rapamycin increases β-amyloid buildup in Alzheimer's disease mouse model

Researchers from The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have found that oral administration of rapamycin to an Alzheimer's disease mouse model causes an increase in beta (β)-amyloid protein plaques. β-amyloid buildup is a hallmark of Alzheimer's disease.
United States Qian Shi Emily Henderson Department Of Cellular Ut Health San Antonio Teresa Lozano Long School Of Medicine

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