Page 140 - Eceptor News Today

Researchers examined the role of sialic acid-binding immunoglobulin-type lectins-1, a myeloid cell-specific receptor, in facilitating SARS-CoV-2 infection of ACE2-deficient macrophages and its effect on pro-inflammatory cytokine expression.

New computational simulations of the behavior of SARS-CoV-1 and SARS-CoV-2 spike proteins prior to fusion with human cell receptors show that SARS-CoV-2, the virus that causes COVID-19, is more stable and slower changing than the earlier version that caused the SARS epidemic in 2003.

A recent study discovered that near relatives of MERS-CoV utilize ACE2 as functional receptors.

Researchers designed nanoparticles representing RBDs of the S protein of animal sarbecoviruses and SARS-CoV-2 to evaluate their potential as a pan-sarbecovirus vaccine candidate.

Researchers examined the unique clusters of monocytes and regulatory T cells in the circulating blood from convalescent COVID-19 patients over a prolonged period after recovery, using scRNA sequencing.

Furin inhibitors as potential therapeutics for treating COVID-19 and other diseases, wherein furin is integral for their pathogenicity and progression.

Researchers proposed rotavirus-based vaccine vectors with the potential for developing polyvalent vaccines targeting multiple enteric viruses, including SARS-CoV-2.

Researchers bioengineered a divalent fusion vaccine by combining the immunogenic region of the nucleocapsid protein and the receptor-binding domain of the spike protein of SARS-CoV-2.

Researchers developed a method for tracking the binding of the receptor-binding domain of SARS-CoV-2 in vivo using genetically engineered extracellular vesicles that can migrate to ACE2 expressing cells.

A recent study analyzed the polymorphisms in the SARS-CoV-2 spike proteins' S1/S2 subunits.