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New method for generating binding proteins solves a long-standing challenge in drug development

A team of scientists has created a powerful new method for generating protein drugs. Using computers, they designed molecules that can target important proteins in the body, such as the insulin receptor, as well as vulnerable proteins on the surface of viruses.
Brian Coventry Longxing Cao David Baker Emily Henderson Scripps Research Institute National Cancer Institute

A novel mRNA vaccine encoding delta RBD induces high neutralizing antibody titers

A team of international scientists has developed an mRNA-based coronavirus disease 2019 (COVID-19) vaccine encoding the receptor-binding domain (RBD) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) delta variant. The vaccine candidate has shown high efficacy in inducing neutralizing antibodies and protecting against delta infection in mice. The study is currently available on theย bioRxiv* preprint server.
Coronavirus Disease Covid 19 Immune Response Ars Cov 2 Evere Acute Respiratory Evere Acute Respiratory Syndrome

Evusheld™ found to poorly neutralize Omicron in kidney transplant patients

Researchers evaluated the neutralizing antibody titers and anti-receptor-binding domain immunoglobulin G titers in sera of kidney transplant recipients who were vaccinated against COVID-19 and treated with 300 mg dosage of Evusheldโ„ข
Michal Bednarek Shutterstock Drug Administration Coronavirus Disease Covid 19 Kidney Transplant Covid 19 Pre Exposure Prophylaxis

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