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Breakthrough research offers hope for patients with persistent Lyme disease symptoms

Tulane University researchers have identified a promising new approach to treating persistent neurological symptoms associated with Lyme disease, offering hope to patients who suffer from long-term effects of the bacterial infection, even after antibiotic treatment.
Geetha Parthasarathy Tulane University Tulane National Primate Research Center Bay Area Lyme Foundation National Institutes Of Health Tulane National Primate Research

Study sheds light on the significance of glucocorticoid receptor in drug-resistant prostate cancer

New research from the University of Eastern Finland sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance could be prevented by limiting the activity of coregulator proteins.
Northern Ostrobothnia Jasmin Huttunen Laura Helminen Cancer Foundation Finland Nucleic Acids Research Academy Research

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Tiam1 inhibition mitigates morphine tolerance and hyperalgesia in mouse model

Morphine and other opioids are vital to treat severe and chronic pain. However, they have two problems -; prolonged use creates morphine tolerance, where ever-increasing doses are needed for the same pain relief, and paradoxically, prolonged use also can create an extreme sensitivity to pain, called hyperalgesia.
United States Baylor College Of Medicine Jun Li Wei Li Xing Fang Lingyong Li

Novel combination therapy shows promise in difficult-to-treat endometrial cancer, study finds

In a small, investigator-initiated phase 2 study by Dana-Farber Cancer Institute investigators, a novel combination of an antibody-drug conjugate and an immune checkpoint inhibitor showed notable activity in pre-treated patients with a difficult-to-treat form of endometrial cancer.
San Diego United States Rebecca Porter American Association For Cancer Research Dana Farber Cancer Institute Farber Cancer

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