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Genetic causes of Raynaud's phenomenon identified

Researchers at Queen Mary University of London’s Precision Healthcare Research Institute (PHURI) and the Berlin Institute of Health (BIH) at Charité – Universitätsmedizin Berlin have identified the genetic causes of Raynaud’s phenomenon. Their findings, published today (12 October) in Nature Communications, could lead to the first effective treatments for people with Raynaud’s.
United Kingdom Lily Ramsey Maik Pietzner Emma Blamont Claudia Langenberg Nature Communications

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Gut defenders: How T-cell intraepithelial lymphocytes guard against colon cancer

In the latest research published in Science Immunology, experts delve into the gene expression patterns of distinct intraepithelial lymphocyte populations in various gastrointestinal tract regions. Key findings reveal the roles of T-cell IELs in detecting infections and ensuring the gut's barrier integrity, with a special emphasis on their function in combating colon cancer.
Kateryna Kon Shutterstock Kateryna Kon Subunit Oft Cell Receptor Complex Colorectal Cancer Ene Expression Ibonucleic Acid

Decoding the twist: Coronavirus spike proteins reveal their intricate invasion dance

Researchers use cryo-EM and molecular dynamics to reveal conformational changes in the spike proteins of human coronavirus HKU1 upon binding with a receptor. Findings unveil the complexity of beta coronavirus attachment, suggesting a more intricate mechanism of host cell invasion than previously understood.
Middle East Coronavirus Disease Covid 19 Ars Cov 2 Electron Microscopy Evere Acute Respiratory Evere Acute Respiratory Syndrome

Altering certain molecular interactions could yield new strategies for treating prostate cancer

Research led by Mays Cancer Center at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) has discovered that altering certain molecular interactions could yield new strategies for treating prostate cancer and related diseases.
United States Lily Ramsey Zhijie Jason Liu California Institute Of Technology Ut Health San Antonio Duke Cancer Institute At University

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