Researchers design one-step procedure for improving effective of adoptive cell immunotherapy against solid tumors
Researchers developed a one-step method to engineer multifunctional M1 phenotype macrophages.
Source: news-medical.net
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Unveiling hidden threats: clustering loops in CAR-T cells impact cancer therapy
How complementarity-determining region (CDR) loops in the single-chain variable fragment (scFv) influence chimeric antigen receptor (CAR)-T cell behavior.
Gorodenkoff Shutterstock Nature Communications Geneart Thermo Fisher Scientific Graphpad Prism Cancer Therapy Blood Cancer
Source: news-medical.net
Olfactory dysfunction following mild SARS-CoV-2 infection associated with neurological changes in structural connectivity
Researchers investigated the changes in olfactory bulb volume and structural connectivity of the brain in patients with olfactory dysfunction following mild SARS-CoV-2.
Source: news-medical.net
Scientists uncover new molecular targets for cardiovascular regulation
Scientists at City of Hope, one of the largest cancer research and treatment organizations in the United States and a leading research center for diabetes and other life-threatening illnesses, have uncovered new molecular targets on a cell receptor that play a major role in cardiovascular regulation.
United States Nagarajan Vaidehi Lily Ramsey Stephane Laporte Department Of Computational Beckman Research Institute Of City Hope
Source: news-medical.net
How conversion between different types of cell death contributes to disease
Researchers elucidate the role of cell death in the pathogenesis of different diseases.
Kateryna Kon Shutterstock Cell Death Discovery Kateryna Kon Ell Death Drug Discovery Embryonic Development
Source: news-medical.net
Revolutionizing type 2 diabetes treatment: personalized approach shows promise in matching patients with optimal glucose-lowering therapies
A personalized therapy selection algorithm for two diabetes type 2 (T2D) treatment drug classes.
United Kingdom Tayside Fife Anastasiyaartcomma Shutterstock Bayesian Causal Forest Type 2 Diabetes Glucagon Like Peptide 1
Source: news-medical.net
Study explores the diverse expression patterns of T cell priming markers across cancers
A recent study explored transcriptomics of T-cell priming markers (TPMs) across different cancers.
Sciepro Shutterstock Drug Administration Genomic Medicine Cancer Treatment Chimeric Antigen Receptor Colorectal Cancer
Source: news-medical.net
Exploring molecular mechanisms and genetic dysregulation in aging and age-associated diseases
Researchers review existing data on the molecular basis of senescence and neurodegeneration in age-related brain diseases.
High Mobility Group Box Underlying Mechanisms Brain Aging Neurodegenerative Diseases Potential Targets Therapeutic Strategies Using
Source: news-medical.net
The immune-modulatory effect of lenvatinib investigated in new study
Researchers explore the effect of lenvatinib treatment on patients with advanced thyroid cancer.
Source: news-medical.net
The effectiveness of antimicrobial mouthwashes in reducing viral load in saliva of COVID-19 patients
Researchers assess the effectiveness of three types of mouthwash in reducing the viral load of SARS-CoV-2 in the saliva of infected individuals.
Source: news-medical.net