Page 34 - Eceptor News Today

The impact of epigenetic features on breast cancer treatment and outcomes.

Deep-learning technology developed by a team of Johns Hopkins engineers and cancer researchers can accurately predict cancer-related protein fragments that may trigger an immune system response.

A collaborative study between LSU Health New Orleans School of Medicine, the University of Rochester and Cellestia Biotech AG, a biopharmaceutical company headquartered in Basel, Switzerland, provides compelling evidence that combining an investigational oral drug with standard-of-care medications reverts hormone resistance and increases Rx effectiveness in experimental models of estrogen-receptor positive (ER+) and triple-negative breast cancers (TNBC), respectively.

Published online ahead of print in the journal Oncogene , a study led by Josep Villanueva, an Investigator at the Vall d'Hebron Institute of Oncology (VHIO), shows that the receptor for advanced glycation end-product (RAGE) plays a key role in cellular mechanisms of plasticity in mesenchymal triple-negative breast cancer­ (TNBC) that transform epithelial cells into mesenchymal cells as potent drivers of cancer cell proliferation and tumor invasion.

Researchers investigated whether physical and behavioral features among healthcare workers, e.g. nose picking, could increase the risk of SARS-CoV-2 infection.

Researchers performed proteomic Mendelian randomization as well as co-localization analyses to identify drug targets for ovarian cancer.

Researchers describe the virological range of persistent SARS-CoV-2 infection in immunosuppressed individuals.

Researchers investigate whether M2 macrophage-derived exosomes could prevent inflammation-associated damage during sepsis.

The National Cancer Institute (NCI) has awarded a 5-year, $2.7 million grant to researchers at Sanford Burnham Prebys to investigate and elucidate the underlying cellular mechanisms that drive the most common form of breast cancer.

Depression is a complex condition correlated with multiple differences in brain function and mechanisms. A new paper spanning known data about the neurotransmitter GABA and its principal receptors showcases evidence of the receptors' importance in depression and potential as therapeutic targets.