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Study suggests robust lung mucosal immunity against SARS-CoV-2 can be better achieved through hybrid immunity, as opposed to peripheral vaccination alone

Researchers characterized immunological responses by pulmonary mucosal tissues post-COVID-19 vaccination and/or SARS-CoV-2 infection, to assess the impact of hybrid immune protection on the durability of mucosal immunological responses.
Kateryna Kon Shutterstock Industry Focus Coronavirus Disease Covid 19 Ars Cov 2 B Lymphocyte Covid 19

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Direct stochastic optical reconstruction microscopy combined with different labeling approaches for the visualization and quantification of ACE2 on different cells

Researchers performed dSTORM (direct stochastic optical reconstruction microscopy) with several labeling techniques for visualizing and quantifying ACE2 receptor expression on various cells.
Kateryna Kon Shutterstock Industry Focus Coronavirus Disease Covid 19 Ngiotensin Converting Enzyme 2 Fluorescence Imaging Ars Cov 2

New candidate molecule could become an effective non-hormonal male contraceptive

Despite birth control existing for decades, almost none of the options specifically target sperm cells. Researchers are now developing approaches that target testosterone or otherwise interrupt the sperm's ability to fertilize an egg, yet these may not work for everyone.
Gundai Georg Emily Henderson Medicinal Chemistry Industry Focus Birth Control Medicinal Chemistry

Voles can form enduring attachments with mates and provide parental care without oxytocin receptors

The vital role of oxytocin-;the "love hormone"-;for social attachments is being called into question. More than forty years of pharmacological and behavioral research has pointed to oxytocin receptor signaling as an essential pathway for the development of social behaviors in prairie voles, humans, and other species, but a genetic study publishing in the journal Neuron on January 27 shows that voles can form enduring attachments with mates and provide parental care without oxytocin rec...
Devanand Manoli Nirao Shah Devanand Manoli Labmanoli Emily Henderson Burroughs Wellcome Fund Laboratory Of Stanford University

Biology underlying pair bonding and parenting may not be dictated by oxytocin receptors, study shows

Turning a decades-old dogma on its head, new research from scientists at UC San Francisco and Stanford Medicine shows that the receptor for oxytocin, a hormone considered essential to forming social bonds, may not play the critical role that scientists have assigned to it for the past 30 years.
Devanand Manoli Nirao Shah Emily Henderson Weill Institute For Neurosciences Stanford Medicine Love Potion

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