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New therapy-relevant marker may help identify ER+ breast cancer patients who may benefit from immunotherapies

​A multi-institutional team led by scientists from the Medical College of Wisconsin Cancer Center has discovered PD-L2 as a therapy-relevant marker to identify patients with estrogen receptor-positive breast cancer who may benefit from new immunotherapies.
United States San Antonio Susang Komen Hallgeir Rui Emily Henderson Uniformed Services University

Mosaic RBD nanoparticles offer 100% protection against SARS-CoV-2 in animal model

A recent PNAS journal study has sought to address the above-stated drawback and developed a new strategy that involves a self-assembling scaffold of proliferating cell nuclear antigen (PCNA). This technique can develop nanoparticles containing evenly incorporated heterotypic antigens.
Industry Focus Animal Model Coronavirus Disease Covid 19 Ars Cov 2 Ngiotensin Converting Enzyme 2 Covid 19

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Researchers identify a key host-cell player in COVID-19 infections

Researchers at University of California San Diego and UC Riverside have further elucidated the molecular pathway used by the SARS-CoV-2 virus to infect human lung cells, identifying a key host-cell player that may prove a new and enduring therapeutic target for treating COVID-19.
United States San Diego University Of California San Diego Tariq Rana Emily Henderson Institute Of Genomic Medicine

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