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Hybrid immunity from mRNA vaccines and breakthrough Omicron infections induces stronger immune responses against Omicron BQ.1.1

Researchers evaluated plasma samples from individuals vaccinated with a fourth booster dose of mono- or bivalent mRNA SARS-CoV-2 vaccine to evaluate the recognition and neutralization capacity against the ancestral (D614G) strain and the Omicron BQ.1.1 subvariant.
Industry Focus Image Credit Covid 19 Ibonucleic Acid Ars Cov 2 Evere Acute Respiratory

Study reveals protective role of CRTC1 in stopping people from overeating high-calorie foods

High-calorie foods-;high in fat, oil, and sugar-;can taste good but often cause overeating, leading to obesity and major health problems. But what stimulates the brain to cause overeating?
Shigenobu Matsumura Emily Henderson Osaka Metropolitan University School Of Human Life Regulated Transcription Coactivator Associate Professor Shigenobu Matsumura

Targeting Piezo2 could provide new avenue for treating chronic pain related to gastrointestinal disorders

Targeting a receptor responsible for our sense of touch and temperature, which researchers have now found to be present in our colon, could provide a new avenue for treating chronic pain associated with gastrointestinal disorders such as irritable bowel syndrome.
Nick Spencer Emily Henderson Public Health College Of Medicine Professor Nick Spencer At Flinders University Professor Hongzhen Hu At Washington University

Enzyme inhibition reduces cancer-related bone loss and the number of bone metastases

In our bones, specialized cells called osteoblasts are responsible for building up bone substance. A team of researchers led by scientists from the DKFZ-Hector Cancer Institute at the University Medical Center Mannheim and the University Medical Center Hamburg Eppendorf has now identified an enzyme that controls the activity of osteoblasts.
Nordrhein Westfalen Baden Wüberg Eric Hesse Vinh Luu Esteban Masuda Emily Henderson

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Study identifies four new monoclonal antibodies with broad neutralizing potencies that target conserved SARS-CoV-2 epitopes

Researchers described four novel monoclonal antibodies with potent and broad neutralization activity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, including the current globally dominant Omicron BA.4/BA.5.
Corona Borealis Image Credit Discovery Industry Focus Coronavirus Disease Covid 19 Ars Cov 2 Amino Acid

Seroprevalence measurements reveal a higher incidence of asymptomatic SARS-CoV-2 infections among residents of three federal German states

Researchers measured the seroprevalence against SARS-CoV-2 in blood donors from the states of Hesse, Lower Saxony, and North Rhine-Westphalia in Germany to determine the incidence of undetected asymptomatic SARS-CoV-2 infections.
Lower Saxony North Rhine Westphalia Coronavirus Disease Covid 19 Ars Cov 2 Covid 19 Polymerase Chain Reaction

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