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Scientists make breakthrough in understanding how inflammation is regulated

Scientists from Trinity College Dublin have made an important breakthrough in understanding how inflammation is regulated. They have just discovered that a key immune alarm protein previously believed to calm down the immune response actually does the opposite.
Seamus Martin Emily Henderson Trinity College Dublin Smurfit Institute Smurfit Professor Genomics Industry Focus

An assessment of T cell and antibody immunity against SARS-CoV-2 VOCs and the effect of booster shots

A new study in the journal Vaccines aimed to analyze the long-term kinetics of SARS-CoV-2 specific T cell and humoral responses following primary and booster vaccinations in previously infected individuals.
Booster Vaccinations Previously Infected Image Credit Discovery Industry Focus Highern Specifict Cell Coronavirus Disease Covid 19

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Using synthetic gene cir­cuits to better control the timing of immunotherapy

In two separate studies, researchers demonstrate how synthetic biology can be used to tackle a difficult issue in cancer immunotherapy: the way immunotherapy-related approaches focused on short-term killing of tumor cells may fail to eradicate tumors because growth of tumors happens on longer timescales.
Greg Allen Hui Shan Li Emmanuel Salazar Cavazos Emily Henderson Ancer Immunotherapy Immune Response

Study finds anti-S binding antibody levels are a valid correlate of protection against Omicron BA.1/BA.2 infections

Researchers used serological measurements from a longitudinal cohort to evaluate the use of binding antibodies against the SARS-CoV-2 spike protein receptor binding domain as correlates of protection against the immune evasive Omicron subvariants BA.1 and BA.2.
Actionable Register Geneva Outpatients Coronavirus Disease Covid 19 Covid 19 Ars Cov 2 Evere Acute Respiratory

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