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Nanomaterial can indirectly affect the immune system via the gut microbiome, study shows

The nanomaterial graphene oxide-;which is used in everything from electronics to sensors for biomolecules-;can indirectly affect the immune system via the gut microbiome, as shown in a new study on zebrafish by researchers at Karolinska Institutet in Sweden.
Vastra Gotalands Lan Karolinska Institutet Guotao Peng Emily Henderson Institute Of Environmental Medicine Chalmers University Of Technology

Off-the-shelf immunotherapy could offer new hope for patients with hard-to-treat multiple myeloma

A new therapy that makes the immune system kill bone marrow cancer cells was successful in as many as 73 percent of patients in two clinical trials, according to researchers from The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai.
United States Emily Henderson Myeloma Program American Society Of Hematology Icahn School Of Medicine At Mount Sinai Tisch Cancer Institute

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Researchers develop a virtual molecular library of thousands of 'command sentences' for cells

Using new machine learning techniques, researchers at UC San Francisco (UCSF), in collaboration with a team at IBM Research, have developed a virtual molecular library of thousands of "command sentences" for cells, based on combinations of "words" that guided engineered immune cells to seek out and tirelessly kill cancer cells.
Kyle Daniels Simone Bianco Shangying Wang Wendell Lim Sara Capponi Emily Henderson

Addition of capivasertib to fulvestrant doubles progression-free survival in HR-positive breast cancer patients

In patients with hormone receptor (HR)-positive, HER2-negative tumors resistant to aromatase inhibitors, addition of the investigational AKT inhibitor capivasertib to fulvestrant (Faslodex) doubled the median progression-free survival compared with placebo plus fulvestrant in the phase III CAPItello-291 clinical trial, according to results presented at the San Antonio Breast Cancer Symposium, held December 6-10, 2022.
San Antonio United States City Of United Kingdom Nicholas Turner Emily Henderson

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