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Prophylactic administration of SARS-CoV-2 specific immunoglobulin Y generated in chicken eggs displays protective effects in infected mice

A new study characterized and tested the antibody activity of SARS-CoV-2-specific immunoglobulin Y (IgY) derived from the eggs laid by chickens immunized with recombinant SARS-CoV-2 receptor binding domain (RBD) protein.
United States Drug Administration United States Food Coronavirus Disease Covid 19 Ars Cov 2 Covid 19

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Molecular engineered low-cost highly effective RBD-based COVID vaccine

In a recent study posted to the bioRxiv* preprint server, an international team of researchers developed a second-generation severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor binding domain (RBD) antigen (RBD-J6) by molecular engineering with two additional amino acid (aa) substitutions (S383D and L518D mutations) in a hydrophobic cryptic RBD core epitope to enhance stability and expression against SARS-CoV-2 variants of concern (VOCs).
Beta Vocs Coronavirus Disease Covid 19 Amino Acid Aspartic Acid Covid 19 Ars Cov 2

Centessa Pharmaceuticals plc: Centessa Pharmaceuticals Announces Poster Presentation Featuring Novel Orexin Receptor 2 (OX2R) Agonist Discovery Pipeline at the 26th Conference of the European Sleep Research Society (Sleep Europe 2022)

- Data demonstrate potent efficacy of small-molecule OX2R agonists in a non-clinical model of narcolepsy type 1 (NT1) -- Company recognizes World Narcolepsy Day on September 22nd - BOSTON and LONDON
United States City Of United Kingdom Mario Alberto Accardi Orexin Ataxin Saurabh Saha

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