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Rational treatment strategies for SARS-CoV-2 derived from human pluripotent stem cells models

In a recent study posted to the bioRxiv* preprint server, researchers in Australia explored the molecular mechanisms of the pulmonary and cardiac complications caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection using human stem-cell-derived cardiac and lung cells.
Kateryna Kon Coronavirus Disease Covid 19 Ars Cov 2 Stem Cells Covid 19 Magnetic Resonance Imaging

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Resistance of Russian Rhinolophus bats containing ACE2-dependent sarbecoviruses to COVID-19 vaccines

In a new study, researchers investigated the receptor tropism and serological cross-reactivity for spike (S) protein receptor-binding domains from two clade 3 sarbecoviruses found in Russian Rhinolophus (horseshoe) bats.
Khosta Rbds Pseudotyped Vlps Rudmer Zwerver Shutterstock Khostas Rbds Russian Rhinolophus Genomics Industry Focus

Omicron BA.1 breakthrough infection in vaccinated individuals recall memory B cells to confer immunity

In a new study, researchers followed up with individuals vaccinated with a COVID-19 vaccine based on the mRNA platform up to six months following Omicron BA.1 breakthrough infection to trace the evolution of their antibody immunity.
Aimee Molineux Neha Mathur Neha Mathursep Yurchanka Siarhei Shutterstock Coronavirus Disease Covid 19 B Cell

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