Effectiveness Trials News Today

<p>Researchers have reached an agreement on how best to measure the severity and impact of Long COVID by identifying a “Core Outcome Measure Set” (COMS).</p>

BACKGROUND: Malignant bowel obstruction is experienced by 15% of people with advanced cancer, preventing them from eating and drinking and causing pain, nausea and vomiting. Surgery is not always appropriate. Management options include tube or stent drainage of intestinal contents and symptom control using medication. Published literature describing palliative interventions uses a broad range of outcome measures, few of which are patient-relevant. This hinders evidence synthesis, and fails to co...

Peter Hanlon and colleagues conduct meta-analyses of individual participant data extracted from 120 randomised controlled trials to investigate whether comorbidity modifies treatment effects.

OMERACT arose from a need to streamline clinical outcome measures in rheumatology, and now it is bringing its expertise to work with other organizations in clinical areas of common interest

These international, consensus-based, patient-reported outcomes (PRO)–specific guidelines aim to lay out the ethical considerations that researchers, research e

Date Time Long COVID research receives funding boost to advance treatment and diagnostics Imperial academics have received funding from the National Institute of Health Research (NIHR) to support new research into long COVID. Three Imperial projects are among 15 UK-based studies to be backed by £19.6 million in government funding through the NIHR. The research programmes will help to better understand long COVID, improve diagnosis and find new treatments for the condition. Long COVID can have ...