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Researchers develop gene-edited stem cells to reduce arrhythmias in heart attack patients

In a recent study published in the journal Cell Stem Cell, researchers hypothesized that pacemaker-like activity of human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) resulted in engraftment arrhythmias (EAs), which hampers the clinical use of cell-based therapy using hPSC-CMs for treatment of myocardial infarction (MI).
Neha Mathurmay Neha Mathur Cell Stem Heart Attack Stem Cells Ene Expression

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New computational method identifies routes of cellular differentiation in acute myeloid leukemia

Researchers have developed a new method to distinguish between cancerous and healthy stem cells and progenitor cells from samples of patients with acute myeloid leukemia (AML), a disease driven by malignant blood stem cells that have historically been difficult to identify.
Comunidad Autonoma De Cataluna Baden Wüberg Emily Henderson Sergi Beneyto Lars Velten Anne Kathrin Merbach

New genome editing technology achieves efficient and precise large DNA insertions

GAO Caixia's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed a new genome editing technology that achieves efficient and precise targeted insertion of large DNA segments in plants.
Emily Henderson Development Program Of China National Key Research Strategic Priority Research Program Institute Of Genetics Developmental Biology

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