Lars Velten News Today

Researchers have developed a new method to distinguish between cancerous and healthy stem cells and progenitor cells from samples of patients with acute myeloid leukemia (AML), a disease driven by malignant blood stem cells that have historically been difficult to identify.

Cancer stem cells that elude conventional treatments like chemotherapy drive long-term cancer growth and relapse. These cells are difficult to isolate and study because of their low abundance and similarity to other stem cells. Researchers have created a new method that can distinguish cancer stem cells, mature cancer cells and otherwise healthy stem cells based on their genetics and gene expression. The findings open new avenues for cancer research personalised medicine.

Single Cell Transcriptomics Could Help Eradicate Leukemia More Effectively March 1, 2021 Immature blood cells in leukemia [Source: toeytoey2530/Getty Images] Research from an international collaboration shows that a single-cell omics approach can identify mutational status and characterize gene expression in hematopoietic stem cells from acute myeloid leukemia patients and successfully identify disease causing cells. Treatments exist for acute myeloid leukemia (AML), but while these often succ...

Barcelona [Spain], March 1 (ANI): A new study by researchers of the Centre for Genomic Regulation claims to have the potential to boost international research efforts in finding drugs that eradicate cancer at its source.