Page 53 - Ene Expression News Today

Decades of research has shown that limits on calorie intake by flies, worms, and mice can enhance life span in laboratory conditions. But whether such calorie restriction can do the same for humans remains unclear.

Using a technique called spatial transcriptomics, researchers at Karolinska Institutet in Sweden have analyzed the gene expression in the mouse colon and created a map showing where in the tissue individual genes are expressed.

What is going on at the single-cell level in the first days of SARS-CoV-2 infection in the lungs?

Researchers at the University of Toronto and University Health Network have shown how probiotic bacteria in the gut could undermine immunity in pancreatic cancer, pointing toward more personalized cancer treatments.

In a study posted to the bioRxiv* preprint server, a team of researchers from Germany studied the expression data of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection-relevant genes such as angiotensin-converting enzyme 2 (ACE2), transmembrane serine protease 2 (TMPRSS2), and the G-protein coupled receptor Mas in an alcohol-exposed rodent model infected with SARS-CoV-2.

In a recent study posted to the bioRxiv* pre-print server, a team of researchers demonstrated that ubiquitin-specific peptidase 22 (USP22) is a crucial regulator of basal interferon (IFN) signaling in native human intestinal epithelial cells (hIECs).

A new method for mapping gene expression deep in the body could one day be used to track stem cells or cancer therapy

A new method for mapping gene expression deep in the body could one day be used to track stem cells or cancer therapy

Inflammation is a defense mechanism of the body to fight pathogens. However, when it is widespread and excessive, it can aggravate the pathology and even cause death.

In work that will enhance the study of such disparate diseases as stroke and dementia, researchers at UC San Francisco have catalogued all the cells that form the blood vessels of the human brain, along with their locations and the genes transcribed in each.