Page 54 - Ene Expression News Today

In this interview, News-Medical speaks to Dr. Thomas McElrath about his latest research into a maternal-fetal medicine technique for predicting pregnancy health.

Our gut is inhabited by a diverse community of microbes, the gut microbiota. This community, composed of hundreds of different species, is essential to our health: it influences our immune system, protects us from infections, and helps us digest food.

In research recently published in the journal of Science Advances, an interdisciplinary team of researchers from the University of Chicago assessed the potential role of cannabidiol (CBD), a natural product extracted from the cannabis plant, to prevent and inhibit severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections in human cells and mice.

Single-cell sequencing enables scientists to uncover heterogeneity that bulk techniques overlook, bringing clarity, detail, and nuance to studies across a wide range of applications. With this expert overview from Dr. Nicole Abreu, Science & Technology Advisor at 10x Genomics , you can start to explore the ways in which single-cell sequencing could transform your own research. 

A new study investigates whether the proportion of ribosomal genes displaying differential gene expression and differential alternative splicing differed between three betacoronaviruses and six other viruses and bacteria.

Are there any risk factors that predispose patients to severe COVID-19 outcomes? A recent study published in the medRxiv* preprint server sheds light on this popular question. Using a combination of population genetics to single-cell RNA sequencing, European researchers identified the respiratory epithelial cell-specific ELF5 gene as a potential mediator for severe COVID-19 cases.

Many future gene and cell therapies to treat diseases like cancer, rare genetic and other conditions could be enhanced in their efficacy, persistence, and predictability by so-called "genomic safe harbors (GSHs)."

A new study by researchers at The Wistar Institute, an international biomedical research leader in cancer, immunology, infectious disease, and vaccine development, has identified a new potential pathway for developing therapeutics that target Epstein-Barr virus (EBV).

In a new study, researchers used per protocol bronchoalveolar lavage fluid (BALF) samples after intubation to evaluate the transcriptomic profiles of the local pulmonary host responses during early-stage severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (CARDS), non-COVID-19 ARDS, and sepsis.

Scientific evidence supporting the involvement of the enzyme MAPK4 in cancer growth and resistance to certain therapies has been growing quickly. In a current study published in the journal Nature Communications, a team at Baylor College of Medicine and collaborating institutions reports that MAPK4 seems to play an important role in triple-negative breast cancer (TNBC), a devastating disease with limited therapeutic options.