Page 61 - Ene Expression News Today

An inter-university research group has succeeded in constructing the gene expression network behind the vascular development process in plants.

In a new study posted to the medRxiv* preprint server, researchers from the University of Pittsburgh and Barrow Neurological Institute report the results of their analysis of several RNA-Seq studies and used computational approaches to discover potential drugs against COVID-19.

A new medRxiv* preprint reports the immunomodulatory effect of the E484K mutation newly acquired by the United Kingdom (U.K.) variant.

All the cells of an organism share the same DNA sequence, but their functions, shapes or even lifespans vary greatly. This happens because each cell "reads" different chapters of the genome, thus producing alternative sets of proteins and embarking on different paths.

Oncotarget published "Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology" which reported that the authors comprehensively investigated miRNA-193a-3p's mode of action in a panel of human cancer cell lines, with a variety of genetic backgrounds, using 1B3, a synthetic microRNA mimic

Molecular subtype of cancer preferentially affects people with Indigenous ancestry Oncotarget published "Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry " which reported that contrasting with this pattern, the age structure of HCC in Andean people displays a bimodal distribution with half of the patients developing HCC in adolescence and early adulthood. To deepen the understanding of the molecular determi...

Antithrombotic endothelial dysfunction is prevented by Tie2 activation in severe COVID-19 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the novel virus responsible for the ongoing coronavirus disease (COVID-19) pandemic. COVID-19 can cause critical illness characterized by severe pulmonary and extrapulmonary manifestations. The risk of mortality for patients with severe COVID-19 is high. Critical COVID-19 is characterized by thrombotic coagulopathy. Increased levels of D-dimer...

Three-way strategy employed by SARS-CoV-2 during infection A new study exposes how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) tampers with the host cells machinery to outsmart the immune system. The SARS-CoV-2 is the cause of the ongoing coronavirus disease 2019 (COVID-19) pandemic. Worldwide the number of infected cases so far is over 160 million. While many have recovered, over 3.34 million people have lost their lives. So how does the virus invade the human cell at the mole...

Millions of people suffer from psoriasis, a chronic, autoimmune disorder that causes scaly patches on the skin and often precedes psoriatic arthritis. While no cure exists, treatments range from topical creams to injected medications that block inflammation.

Researchers show how low-protein diet during pregnancy can cause kidney problems in babies Besides being underweight, babies born to women whose diet lacked sufficient protein during pregnancy tend to have kidney problems resulting from alterations that occurred while their organs were forming during the embryonic stage of their development. In a study published in PLOS ONE, researchers affiliated with the University of Campinas (UNICAMP) in the state of São Paulo, Brazil, discovered the caus...