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Troubled immune system a driver of common eye disease in horses - review

A complex interplay of several dysregulated mechanisms related to the immune system appears responsible for the development of equine recurrent uveitis (ERU), according to the authors of a review. The immune-mediated disease affects the eyes of horses around the world, ultimately leading to blindness. It is characterized by painful, inflammatory bouts alternating with periods of quiescence (causing no trouble or symptoms). During the course of the disease, both eyes can eventually be affected a...
Cornelia Deeg Roxane Degroote Veterinary Medicine Immunological Insights Equine Recurrent Creative Commons License

Researchers look to the gut in investigating debilitating eye condition in horses

Horsetalk.co.nz Researchers look to the gut in investigating debilitating eye condition in horses Scientists have found no evidence of changes in the gut bacteria of horses that may be a factor in equine recurrent uveitis, but say more research in the area is warranted. Equine recurrent uveitis is an immune-mediated disease characterized by recurrent episodes of inflammation within the eye. The condition has an estimated prevalence of 1 to 2% in the United States. Despite being a major...
United States Ralph Hamor Jennifer Macnicol Diego Gomez Caryn Plummer University Of Florida

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