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Researchers unveil mechanism enhancing cellular fitness against aging and neurodegeneration

Researchers at Duke University Medical Center discover a mechanism to enhance the fitness of cells against aging and neurodegenerative diseases. This finding will pave the way for novel therapeutic approaches in neuroprotection against aging-related disorders and neurodegeneration.

United-states
Duke-university
North-carolina
Duke-university-medical-center
Researchers-at-duke-university-medical-center
University-medical
Paulo-ferreira
Age-related-macular-degeneration
Amyotrophic-lateral-sclerosis
Aging
Eurodegeneration

High-fat diet accelerates aging-related memory loss in rats

Study found that a high-fat diet exacerbates age-related cognitive decline in rats, even when microglia cells are removed from the equation, suggesting other pathways may play a role.

Aging
Iet
Icroglia
Nxiety
Lood
Lood-pressure
Ody-mass-index
Rain
Ancer
Ardiovascular-disease
Epression

Genes affecting worm behavior found to be relevant to neurological disease in humans

As an undergraduate student in The University of Texas at Arlington's Honors College, Hannah Selvarathinam knew she wanted to conduct research. Near the end of her first year at UTA, the Keller native reached out to the lab of biology Assistant Professor Piya Ghose.

Texas
United-states
Piya-ghose
Hannah-selvarathinam
University-of-texas-at-arlington
Ghose-lab
Honors-college
Assistant-professor-piya
Assistant-professor
Brain
Brain-disease
Ell

New study reveals potential cellular mechanism behind cognitive decline in Alzheimer's

Researchers have developed a robust method for identifying rare brain neurons that re-enter the cell cycle, offering insights into their role in cognitive disorders such as Alzheimer's disease.

Aging
Rain
Ell
Cell-cycle
Eurodegeneration
Ell-division
Ycling
Na
Na-synthesis
Ene
Ene-expression

Neurons re-entering cell cycle succumb to senescence in neurodegenerative diseases

Post-mitotic neurons in the brain that re-enter the cell cycle quickly succumb to senescence, and this re-entry is more common in Alzheimer's disease, according to a new study published April 9th in the open-access journal PLOS Biology by Kim Hai-Man Chow and colleagues at the Chinese University of Hong Kong.

Kim-hai
Chinese-university-of-hong-kong
Kim-hai-man-chow
Chinese-university
Hai-man-chow
Brain
Ell
Cell-cycle
Eurons
Ging
Lzheimer-39s-disease
Ioinformatics

Cytokine interferon-gamma can be a disease-modifying therapeutic target in multiple system atrophy

Multiple system atrophy is a rare and fatal neurodegenerative disease, where insoluble inclusions of the protein alpha-synuclein appear in oligodendrocyte cells of the brain.

Tempe
Arizona
United-states
Phoenix
Nikhita-mudium
Nicolej-corbin-stein
Acta-neuropathologica
Jeffreyh-kordower
Jhodim-webster
Fredricp-manfredsson
Asta-zane
Rajesh-gupta

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