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Venetoclax regimen not superior to standard therapy alone for older patients with CLL

CHICAGO — The addition of venetoclax to ibrutinib and obinutuzumab did not extend PFS among older patients with treatment-naive chronic lymphocytic leukemia during the COVID-19 pandemic, according to data presented at ASCO Annual Meeting. Long-term follow-up of the phase 3 study is underway to determine potential advantages of the three-drug combination in other settings, researchers wrote.
United States Mindy Valcarcel Ibrutinib Imbruvica Bymatthew Shinkle Jennifera Woyach Ohio State University Comprehensive Cancer Center
Source: healio.com

'Significant progress' in mantle cell lymphoma leads to recent approvals

In this video, Matthew Matasar, MD, chief of the division of blood disorders at Rutgers Cancer Institute, discusses mantle cell lymphoma research presented at ASCO Annual Meeting. Increasing interest in the development of new therapies for mantle cell lymphoma, such as chimeric antigen receptor T-cell therapy and bispecific antibodies, has been fueling research, Matasar said.
Mindy Valcarcel Bymatthew Matasar Matthew Matasar Rutgers Cancer Institute Eli Lilly Co Kite Pharma Gilead Sciences
Source: healio.com

Phone Menu Test Detects Who May Be at Risk of

A new study by investigators from Mass General Brigham has found that a brief, simulated task of navigating a phone menu can detect the earliest changes in daily functioning in people at risk of developing Alzheimer’s disease. Investigators found that an older adult’s performance on the test, which can be completed in a matter of minutes, was associated with the hallmarks of Alzheimer’s disease pathology, including amyloid and tau depositions in the brain. The findings, which were publishe...
United States Chris Gonzalez Rebecca Amariglio Eli Lilly Department Of Neurology At Brigham Eisai Inc

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