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November 10, 2023
The causal links between pro-inflammatory cytokine expression and migraine.
October 24, 2023
The study explores the interconnected risks between COVID-19 and Alzheimer's Disease (AD), highlighting how SARS-CoV-2 can aggravate AD pathology through neuroinflammation and neurodegeneration. It raises significant concerns about the long-term cognitive implications of COVID-19, especially among those already at risk for AD.
August 1, 2023
A recent study elucidated the molecular mechanisms of drug-induced regulation of growth differentiation factor 15 (GDF15).
May 25, 2023
In this application note, Sartorius emphasizes the importance of understanding the complex response of tumor cells, particularly glioblastomas, to cytotoxic chemotherapeutic compounds in neuro-oncology research. The Incucyte ® AI Cell Health Analysis Software Module accurately segments and classifies individual cells as live or dead using pre-trained neural networks. This approach enables ef
May 23, 2023
In this application note, Sartorius demonstrates a robust in vitro assay using the Incucyte ยฎ Live-Cell Analysis System and AI-driven analytics to assess the cytotoxic effects of chemotherapeutics in glioblastoma multiform (GBM) cells. The study shows concentration-dependent effects across different glial cell types and highlights the systems potential for screening therapeutic candidates. The Incucyte system offers automated analysis, accurate cell segmentation, and live/dea
May 12, 2023
Glioblastoma cancer cells use mitochondria from the central nervous system to grow and form more aggressive tumors, according to new Cleveland Clinic-led findings published in Nature Cancer.
January 11, 2023
There are two fundamentally different cell types in the brain, neurons and glial cells. The latter, for example, insulate the "wiring" of nerve cells or guarantee optimal working conditions for them.
September 10, 2022
Researchers from Dresden uncover a greater neuron production in the frontal lobe during brain development in modern humans than Neandertals, due to the change of a single amino acid in the protein TKTL1.
April 11, 2022
In recognition of World Parkinson's Day, we speak to Dr. Arthur Roach, Director of Research at Parkinsonโs UK, about the current Parkinson's landscape.
March 18, 2022
Mechanism by which the neuronal maturation and synaptic pruning of newborn neurons (via microglia) occurs has been discovered.