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COVID-19 increases Alzheimer's risk

The study explores the interconnected risks between COVID-19 and Alzheimer's Disease (AD), highlighting how SARS-CoV-2 can aggravate AD pathology through neuroinflammation and neurodegeneration. It raises significant concerns about the long-term cognitive implications of COVID-19, especially among those already at risk for AD.
Alzheimer 39s Disease Coronavirus Disease Covid 19 Glial Cell Public Health Ars Cov 2 Evere Acute Respiratory

Quantifying chemotherapeutic cytotoxicity in glial cells using AI-driven label-free cell analysis

In this application note, Sartorius emphasizes the importance of understanding the complex response of tumor cells, particularly glioblastomas, to cytotoxic chemotherapeutic compounds in neuro-oncology research. The Incucyte ®  AI Cell Health Analysis Software Module accurately segments and classifies individual cells as live or dead using pre-trained neural networks. This approach enables ef
Ai Cell Health Analysis Software Module Application Note Health Analysis Software Module Glial Cell Incucyte

AI-driven label-free image analysis for assessing chemotherapeutic cytotoxicity in glial cells

In this application note, Sartorius demonstrates a robust in vitro assay using the Incucyte ยฎ Live-Cell Analysis System and AI-driven analytics to assess the cytotoxic effects of chemotherapeutics in glioblastoma multiform (GBM) cells. The study shows concentration-dependent effects across different glial cell types and highlights the systems potential for screening therapeutic candidates. The Incucyte system offers automated analysis, accurate cell segmentation, and live/dea
Application Note Live Cell Analysis System Glial Cell Incucyte

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Single amino acid change in TKTL1 protein underlies greater neuron production in modern humans than Neandertals

Researchers from Dresden uncover a greater neuron production in the frontal lobe during brain development in modern humans than Neandertals, due to the change of a single amino acid in the protein TKTL1.
Pauline Wimberger Anneline Pinson Wieland Huttner Emily Henderson Max Planck Institute Of Molecular Cell Biology University Hospital Dresden

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