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Analyzing pathogenic mechanism in Hailey-Hailey Disease patients by using cycloheximide chase assay, CCK8 assay and in silico modeling of SPCA1 mutant

West Africa has recorded a relatively higher proportion of asymptomatic coronavirus disease 2019 (COVID-19) cases than the rest of the world, and West Africa-specific host factors could play a role in this discrepancy. Here, we assessed the association between COVID-19 severity among Ghanaians with their immune profiles and ABO blood groups. Plasma samples were obtained from Ghanaians PCR-confirmed severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive individuals. The participant...

Examining the greater plasma protein adsorption on MSN leads to serious inflammatory reactions in (DFE)-induced mouse atopic dermatitis. Click to read more...

Background Patients with chronic kidney disease and undergoing hemodialysis are at greater risk of developing COVID-19. In spite of vaccine efficacy, SARS-CoV-2 breakthrough infection has been reported in several studies. This study was carried out to assess if seroconversion could predict SARS-CoV-2 breakthrough infection in a cohort of vaccinated patients undergoing hemodialysis. Methodology Patients undergoing maintenance hemodialysis for at least three months and who had received two doses o...

Several interventions have shown benefits in improving mental health problems such as depression which is common in people living with HIV. However, there is a paucity of evidence on the effect of these interventions in improving HIV treatment outcomes. This study aimed at bridging this evidence gap and guiding the integration of depression and HIV management, particularly in rural health settings of Cameroon. We carried out a cluster-randomized intervention study targeting persons aged 13&n...

To determine which of these particles is primarily involved in releasing of HCC-specific biomarker glypican-3 (GPC3) when autophagy is impaired.

Determining platelet counts in Malawian children and in adults during acute P. falciparum malaria and a month post treatment. Click to read..

Effects of sinomenine on orthodontic tooth movement & root resorption in rats, as well as the effect of sinomenine on the osteogenesis PDLSCs.

In vivo detection of macromolecule free radicals in mouse septic associated encephalopathy using a new strategy of MRI and immunospin trapping. Click to read..

Evaluating the synergistic effect of linezolid and fosfomycin on fosfomycin-sensitive and -resistant Enterococcus clinical isolates in vitro and in vivo