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Exploring photocatalytic Cu2WS4 nanocrystals for efficient bacterial killing and biofilm disruption to develop a novel strategy for wound infection care.

G-Rb1 exerts anti-inflammatory and anti-fibrotic activities in vivo and in vitro by suppressing the activation of the NLRP3 inflammasome and NF-κB pathway

Brucellosis poses a serious threat to human and animal health, particularly in developing countries such as China. The Inner Mongolia Autonomous Region is one of the most severely brucellosis-endemic provinces in China. Currently, the host immune responses functioning to control Brucella infection and development remain poorly understood. The aim of this study is to further clarify the key immunity characteristics of diverse stages of brucellosis in Inner Mongolia. We collected a total of 733 bl...

Melatonin suppresses NLRP3 inflammasome activation via TLR4/NF-κB and P2X7R signaling in high-fat-diet induced murine NASH model

Significance Statement Proinflammatory macrophages that infiltrate the kidney after ischemia-repe

Exploring the potential impact of adiponectin in the pathogenesis of diabetic retinopathy

Investigating whether Z-Guggulsterone can relieve neuropathic pain in sciatic nerve chronic constriction injury mice by inhibiting the expression of cytokines.

Background As the prevalence of COVID-19 recovery cases increased, patients started to notice new symptoms after being cured of the acute infection. We aimed to study the type of persistent symptoms post-COVID-19 infection, their prevalence, and factors that play a role in developing the post-COVID-19 symptoms among COVID-19 patients at King Abdulaziz Medical City, Jeddah, Saudi Arabia. Methods A cross-sectional study was conducted at King Abdulaziz Medical City, Jeddah, Saudi Arabia, from the p...

Aortic aneurysm (AA) is a global public health concern. However, little is known about the disease burden of AA in China. Following the general analytic strategy used in the Global Burden of Disease Study (GBD) 2019, we analyzed the mortality and years of life lost (YLLs) due to AA, stratified by sex, age, and province-level region in China from 1990 to 2019. The temporal trend of AA burden in China was analyzed and the main attributable risk factors for AA in China were also explored. In China,...

Significance Statement Alport syndrome (AS), a genetic disorder of the glomerular basement membra