Emory faculty and staff are frequently recognized for their work locally, nationally and internationally. Read a sampling of recent accolades, including awards for professional contributions and leadership appointments.
A small molecule inhibitor shows promise to reduce the growth of uveal melanoma
Uveal melanoma, or UM, is a rare and deadly cancer of the eye, and the mortality rate has remained unimproved for 40 years. Half of the melanomas spread to other organs of the body, causing death in less than a year, so new treatments to preserve vision and prevent death are an urgent need.
Now a preclinical study by researchers at the University of Alabama at Birmingham and Emory University, Atlanta, offers hope a small molecule inhibitor has been identified that dampens the potent drivers of this tumor. In mouse models, the inhibitor, KCN1, strongly limited primary disease in the eye and metastatic tumor dissemination to the liver, and animals survived longer, without overt side effects.
Melanoma of the eye: Preclinical tests show path toward treatment eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.