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AI can help doctors make better decisions and save lives

Deploying and evaluating a machine learning intervention to improve clinical care and patient outcomes is a key step in moving clinical deterioration models from byte to bedside, according to a June 13 editorial in Critical Care Medicine that comments on a Mount Sinai study published in the same issue.
New York United States Horacew Goldsmith Arash Kia Roopa Kohli Seth Davidl Reich

Altering cellular interactions around amyloid plaques may offer novel Alzheimer's treatment strategies

Researchers at the Icahn School of Medicine at Mount Sinai have made a significant breakthrough in Alzheimers disease research by identifying a novel way to potentially slow down or even halt disease progression. The study, which focuses on the role of reactive astrocytes and the plexin-B1 protein in Alzheimers pathophysiology, provides crucial insights into brain cell communication and opens the door to innovative treatment strategies. It was published in Nature Neuroscience on May 27.
Hongyan Zou Roland Friedel Icahn School Of Medicine At Mount Sinai Icahn Mount Sinai Bin Zhang Icahn Mount

Two new studies offer insights into the molecular biology of neuropsychiatric disease

Working under the umbrella of the PsychENCODE Consortium, the mental health research project established in 2015 by the National Institutes of Health, a team of Mount Sinai scientists has uncovered important new insights into the molecular biology of neuropsychiatric disease through two new studies published in a special issue of Science on Friday, May 24.
Biao Zeng Panos Roussos John Fullard Nash Family Department Of Neuroscience Mindich Child Health Department Of Genetics

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AI can help improve ER admission decisions

Generative artificial intelligence (AI), such as GPT-4, can help predict whether an emergency room patient needs to be admitted to the hospital even with only minimal training on a limited number of records. In the retrospective study, the researchers analyzed records from seven hospitals, using both structured data, such as vital signs, and unstructured data, such as nurse triage notes, from more than 864,000 emergency room visits while excluding identifiable patient data.
Eyal Klang Ganesh Raut Brendan Carr Donald Apakama Girishn Nadkarni Alexanderw Charney

Two studies offer key insights into the origins and potential treatment of mental health disorders

Working under the umbrella of the PsychENCODE Consortium, the mental health research project established in 2015 by the National Institutes of Health, a team of Mount Sinai scientists has uncovered important new insights into the molecular biology of neuropsychiatric disease through two new studies published in a special issue of Science on May 24.
Jessica Johnson John Fullard Biao Zeng Panos Roussos Nash Family Department Of Neuroscience Department Of Psychiatry

Generative AI enhances ER admission predictions with minimal training

Generative artificial intelligence (AI), such as GPT-4, can help predict whether an emergency room patient needs to be admitted to the hospital even with only minimal training on a limited number of records, according to investigators at the Icahn School of Medicine at Mount Sinai.
Robert Freeman Brendan Carr Donald Apakama Ganesh Raut Girishn Nadkarni Benjamins Glicksberg

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