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IJMS | Free Full-Text | Functional Characterization of Mouse and Human Arachidonic Acid Lipoxygenase 15B (ALOX15B) Orthologs and of Their Mutants Exhibiting Humanized and Murinized Reaction Specificities

The arachidonic acid lipoxygenase 15B (ALOX15B) orthologs of men and mice form different reaction products when arachidonic acid is used as the substrate. Tyr603Asp+His604Val double mutation in mouse arachidonic acid lipoxygenase 15b humanized the product pattern and an inverse mutagenesis strategy murinized the specificity of the human enzyme. As the mechanistic basis for these functional differences, an inverse substrate binding at the active site of the enzymes has been suggested, but experim...
Baden Wüberg Bergisch Gladbach Nordrhein Westfalen United States Miltenyi Biotec Gmb Santa Clara
Source: mdpi.com

Image Analyzer Extends Technology Partnership with OpenText | EFE Comunica

Visual threat intelligence technology now integrated into OpenText Magellan Risk Guard to aid corporate risk management and compliance London | April 26, 2022 . Image Analyzer Extends Technology Partnership with OpenText | EFE Comunica | Agencia EFE
United Kingdom Muhi Majzoub Company Website Technology Supply Agreement European Union Digital Services Eu Digital Services
Source: efe.com

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Spark Cyto

Rating: Application Area:HTS for drugs (70.000 compounds) and gene function (RNAi & CRISPR-Cas) "This detection system nicely bridges the gap between a plate reader and imaging systems like automated microscopes. It combines multi parameter screening (all kinds of fluorescence detection) with the features of image based screening (cytometric measurements) in one machine. Coupling kinetic measurements over long time periods to injection of reagents at the most effective time points wit...
Spark Cyto Image Analyzer Real Time Experimental Control தீப்பொறி சைட்டோ படம் பகுப்பாய்வி ரியல் நேரம் சோதனை கட்டுப்பாடு

AWS urges US court to throw out Parler breach of contract lawsuit

AWS urges US court to throw out Parler breach of contract lawsuit Amazon Web Services has responded to news of Parler’s attempt to sue it for breach of contract by filing a lawsuit detailing allegations of the various threats it claims forced it to pull the plug on the stricken social media site Share this item with your network: By Published: 14 Jan 2021 12:45 Amazon Web Services (AWS) has urged the United States District Court to dismiss Parler’s application to have its service reins...
Capitol Hill District Of Columbia United States Us Communications Decency Amazon Web Services United States District Court

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