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Primate model unlocks clues to long-COVID's impact on blood sugar, hints at vaccine benefits

The study uses a non-human primate model to explore the link between long-COVID and disruptions in glucose metabolism, finding a positive correlation. Vaccination appeared to improve glycemic control, suggesting a possible role in managing long-COVID symptoms.
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Frontiers | Chronic Obstructive Pulmonary Disease Patients Have Increased Levels of Plasma Inflammatory Mediators Reported Upregulated in Severe COVID-19

2Informatic Unit, INMEDIT SAS and Faculty of Engineering, University of Cartagena, Cartagena, Colombia 3Clinica Respiratoria y de Alergias, Cartagena, Colombia 4Departamento de Investigaciones, Fundación Cardioinfantil, Bogotá, Colombia 5Research Department - CINEUMO, Fundación Neumológica Colombiana, Bogotá, Colombia 6Research Department and Specialization Program in Pulmonology, Universidad de la Sabana, Bogotá, Colombia Background: Chronic obstructive pulmonary disease (COPD) is associ...
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Researchers take steps to standardize correlates of protection against SARS-CoV-2

Researchers take steps to standardize correlates of protection against SARS-CoV-2 Researchers in the UK and Germany have identified a range of assays and biomarkers of humoral (antibody) immunity against coronavirus disease 2019 (COVID-19) that can be used to define correlates of protection in future studies. Wherever suitable, antibody-based parameters were expressed in International Units (IU) and Binding Antibody Units (BAU). "The adoption of common results reporting unitage in IU and BAU as...
United Kingdom Sally Robertson Jonathan Heeney International Units University Of Cambridge World Health Organization

Study attempts to standardize humoral immune Correlates of Protection (CoP) in COVID-19

Study attempts to standardize humoral immune Correlates of Protection (CoP) in COVID-19 The World Health Organization (WHO) declared the coronavirus disease 2019 (COVID-19) pandemic in March 2020, owing to the rapid worldwide spread of its causative virus: severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). This is a positive-sense RNA virus that causes mild to critical infection. Several COVID-19 vaccines have received emergency authorization by national regulatory authorities in dif...
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Preclinical study from NIH/Moderna: Correlates of SARS-CoV-2 immunity in non-human primates

Preclinical study from NIH/Moderna: Correlates of SARS-CoV-2 immunity in non-human primates Researchers in the United States have shown that the antibody response induced by the Moderna mRNA-1273 vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a correlate of immune protection against coronavirus disease 2019 (COVID-19) in non-human primates. “A critical issue for optimizing the use of COVID-19 vaccines is defining an immune correlate of protection,” says Robe...
National Institutes Of Health United States Robert Seder Sally Robertson National Institutes Immune Correlates

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