Interventional Trials News Today

INTRODUCTION: Sustainable approaches to support care coordination and symptom management needs of critically ill adults living with multimorbidity are needed to combat the challenges and complexity that multimorbidity presents. The study aims to test the feasibility of the Care cOORDInatioN And sympTom managEment (COORDINATE) intervention to improve health outcomes of adults living with multimorbidity. METHODS AND ANALYSIS: A multicomponent nurse-driven intervention was developed using experienc...

This article provides an extension of the Consolidated Standards of Reporting Trials 2010 checklist for the reporting of factorial trials.

The CONSORT (CONsolidated Standards Of Reporting Trials) 2010 statement is the standard guideline for reporting completed randomised trials. The CONSORT Dose-finding Extension (DEFINE) extends the guidance (with 21 new items and 19 modified items) to early phase dose-finding trials with interim dose escalation or de-escalation strategies. Such trials generally focus on safety, tolerability, activity, and recommending dosing and scheduling regimens for further clinical development. These trials a...

SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) 2013 provides guidance for clinical trial protocol writing. However, neither the original guidance nor its extensions adequately cover the features of early phase dose-finding trials. The SPIRIT Dose-finding Extension (DEFINE) statement is a new guideline that provides recommendations for essential items that should be provided in the protocols of these trials. It details extensions to the SPIRIT 2013 guidance, incorpora...

Apples are rich in fiber and protective components. Fruits are an important part of any diet. But are apples good for weight loss in AU 2023?

Apples are rich in fiber and protective components. Fruits are an important part of any diet. But are apples good for weight loss in UK 2023?

Apples are rich in fiber and protective components. Fruits are an important part of any diet. But are apples good for weight loss 2023?

The Latest released Clinical Trials Market Research Report provides a detailed assessment of Key and emerging players showcasing company profiles, product/service offerings, market price, and sales revenue to better derive market size estimation. The most appropriate, exclusive, realistic, and admirable Clinical Tri...

Data Bridge Market Research has unveiled a new report called "Immuno-Oncology (IO) Market" which provides an in-depth exploration of growth strategies, drivers,

The best elderberry supplement contains beneficial ingredients that boost your immune system and benefit your general health in 2023.