"Bioengineering clinically relevant cardiomyocytes and cardiac tissues " by Emma Claire James, Eva Tomaskovic-Crook et al.
The regenerative capacity of cardiomyocytes is insufficient to functionally recover damaged tissue, and as such, ischaemic heart disease forms the largest proportion of cardiovascular associated deaths. Human-induced pluripotent stem cells (hiPSCs) have enormous potential for developing patient specific cardiomyocytes for modelling heart disease, patient-based cardiac toxicity testing and potentially replacement therapy. However, traditional protocols for hiPSC-derived cardiomyocytes yield mixed...
Cardiac Tissue Electrical Stimulation Human Pluripotent Stem Cells Regenerative Therapy Issue Modelling
Source: uow.edu.au