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In Down syndrome cells, genome-wide disruptions mimic a senescence-like state

The disruption of gene transcription and cell function in Down syndrome is very similar to that seen in cellular aging, MIT scientists find. They used anti-senescence drugs to correct the errors in cell cultures, establishing senescence as a potentially targetable mechanism for future treatment.
United States Ashley Watson Lindsey Guerin Angelika Amon Asaf Marco Vishnu Dileep
Source: mit.edu

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