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IMAGE: The dECM-MA derived from porcine skeletal muscles is combined with PVA fibrillation, which provides the topographical cues for proper cellular alignment when bioengineering rat muscles. view more
Credit: Sang Jin Lee
WASHINGTON, May 11, 2021 When trauma, illness, or injury causes significant muscle loss, reconstructive procedures for bioengineering functional skeletal muscles can fall short, resulting in permanent impairments.
Finding a synergy in the importance of biochemical signals and topographical cues, researchers from Wake Forest Institute for Regenerative Medicine, Sungkyunkwan University, and Chonnam National University developed an efficient technique for muscle regeneration and functional restoration in injured rats. They describe results from the technique in the journal
WashingtonUnited-statesAnthony-atalaJamesj-yooGeun-hyung-kimHyeongjin-leeJiun-leeKwonjin-kimJin-leeSungkyunkwan-universityWake-forest-institute-for-regenerative-medicineChonnam-national-universityCombination of 2-Photon 3D-printer and bioink allows precise, direct printing of living cells
Apr 16 2021
The combination of a 2-Photon 3D-printer with an innovative hydrogel-based bioink allows the direct printing of 3D structures containing living cells at both the meso- and microscale. Developed by UpNano GmbH (Vienna, Austria), the NanoOne Bio is a printer based on the successful NanoOne range of laser-powered 2-Photon 3D-printers that are able to build structures across 12 orders of magnitude. The new hydrogel has been developed with Xpect INX (Ghent, Belgium), a spin-off in foundation specialized in the development of biocompatible materials for the 3D-(bio-)printing industry. It is the only commercially available resin that allows embedding living cells straight from a culture plate within highly precise 3D-printed structures for biological applications.
AustriaBelgiumDenise-mandtJamesj-yooUpnano-gmbPeter-gruberNanoone-bioJasper-van-hoorickBusiness-developmentUpnano-gmbhVan-hoorickWake-forest-institute