Janel Kopp News Today

High insulin levels directly linked to pancreatic cancer. First detailed explanation of why people with obesity and Type 2 diabetes are at an increased risk of pancreatic cancer

In a new study in mouse models, researchers explain the mechanism by which high levels of insulin can contribute to the development of pancreatic cancer.

A new study from researchers at the University of British Columbia's Faculty of Medicine reveals a direct link between high insulin levels, common among patients with obesity and Type 2 diabetes, and pancreatic cancer.

Pancreatic cancer is the fifth biggest cancer killer in the UK, with 9,000 deaths every year.

People with obesity and type 2 obesity are more likely to get pancreatic cancer due to high insulin levels

The first detailed explanation of why people with obesity and Type 2 diabetes are at an increased risk of pancreatic cancer has been published in Cell Metabolism. The research demonstrates that excessive insulin levels overstimulate pancreatic acinar cells, which produce digestive juices. This overstimulation leads to inflammation that converts these cells into precancerous cells.The researchers say the findings may have implications for other cancers associated with obesity and Type 2 diabetes,...

Pancreatic cancer is the fifth biggest cancer killer in the UK, with 9,000 deaths every year.