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Uplizna reduces IgG4 related disease flare risk by 87% in MITIGATE trial

The monoclonal antibody Uplizna met key endpoints in a phase 3 trial for the treatment of IgG4-related disease, marking the first time a placebo-controlled study has shown benefit in the condition, according to a press release from Amgen.Topline results from the double-blind, randomized trial, called MITIGATE, demonstrated an 87% reduced risk for IgG4-related disease (IgG4-RD) flare in patients
United States Jay Bradner Shenaz Bagha Zachary Wallace Massachusetts General Hospital
Source: healio.com

Baystreet.ca - Advancements in Cancer Therapeutics: What to Expect from the Upcoming 2024 Oncology Conference

USA News Group News Commentary – As the 2024 American Society of Clinical Oncology (ASCO) annual meeting approaches, excitement builds over the latest in cancer treatment advancements, particularly in Antibody-Drug Conjugates (ADCs). From May 31 ...
United States Matt Coffey Levi Garraway Jay Bradner Thomas Heineman National Cancer Institute

F. Hoffmann-La Roche Ltd: Roche granted FDA Breakthrough Device Designation for blood test measuring Lp(a) - a key marker for hereditary cardiovascular risk

Approximately one in five people worldwide have elevated Lp(a) levels, putting them at increased risk of cardiovascular diseases including myocardial infarction and stroke.1The Roche Diagnostics Tina-quant®
United States Matt Sause Sabine Borngr Karsten Kleine Rebekka Schnell Simon Goldsborough

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