John Essigmann News Today

Autosomal dominant polycystic kidney disease (ADPKD), the most common form of polycystic kidney disease, can lead to kidney enlargement and eventual loss of function.

A compound originally developed as a cancer treatment may hold promise for treating polycystic kidney disease (ADPKD), which affects more than half a million Americans and can lead to kidney enlargement and loss of function.

ADPKD, the prevalent form of polycystic kidney disease, causes kidney enlargement, often leading to function loss.

ADPKD, the prevalent form of polycystic kidney disease, causes kidney enlargement, often leading to function loss.

 E-Mail CAMBRIDGE, MA -- In the past few years, several medications have been found to be contaminated with NDMA, a probable carcinogen. This chemical, which has also been found at Superfund sites and in some cases has spread to drinking water supplies, causes DNA damage that can lead to cancer. MIT researchers have now discovered a mechanism that helps explain whether this damage will lead to cancer in mice: The key is the way cellular DNA repair systems respond. The team found that too littl...

Credits: Image: MIT News, with DNA images from iStockphoto Previous image Next image In the past few years, several medications have been found to be contaminated with NDMA, a probable carcinogen. This chemical, which has also been found at Superfund sites and in some cases has spread to drinking water supplies, causes DNA damage that can lead to cancer. MIT researchers have now discovered a mechanism that helps explain whether this damage will lead to cancer i...

Credits: Image: Sean Clarke Next image Last fall, seniors in the MIT Department of Biological Engineering (BE) took on the most relevant of all possible design challenges — the Covid-19 pandemic. The capstone design class in the Course 20 major, class 20.380 (Biological Engineering Design) has a different theme every semester, and in September there was little doubt about this fall’s topic — Addressing the Pandemic with BE. “We werent sure how students ...