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Multiple immune reactions when transplanting cartilage into monkeys

Kyoto University The Noriyuki Tsumaki lab reports the effects of gene editing monkey iPS cells on regenerative medicine for damaged knee cartilage. Immune rejection is one of the biggest obstacles to a cell therapy. To solve this problem, researchers have been investigating iPS cells that have been gene edited so that they can evade the immune system. While this concept is theoretically possible, there is limited evidence that it works in species resembling humans. A new study by th...
Yuki Okutani Noriyuki Tsumaki Akihiro Yamashita Kengo Abe Shuichi Matsuda Miho Morioka

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