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KING SKYFRONT, Japan publishes the March 2021 issue of Kawasaki SkyFront i-Newsletter

Improving intellectual property creation and management in R&D A case study of a Japanese funding program leads to suggestions for optimizing scientific and technological innovation Generating and managing intellectual property is an important aspect of research and development (R&D), traditionally carried out in industrial laboratories. At the same time, innovation is often achieved through collaboration between academia, industry and government. Optimal intellectual property management is the...
Kawasaki Ku Kawasaki Shi Shuto Miyashita Yoshimi Yashiro Professoryoshimi Yashiro Innovation Policy Research

Nanomedicine activation profile determines efficacy depending on tumor c-Myc expression

It is known that c-Myc is involved in cancer cell proliferation and angiogenesis and changes the cell cycle, suppresses normal cell differentiation, and promotes cancer metastasis. It is a typical proto-oncogene that regulates many genes related to growth factors and is known to be involved in developing of many cancers, such as chromosomal translocation in Burkitt lymphoma. Therefore, drug discovery research is being conducted worldwide as an anticancer drug targeting this transcription factor...
Tatsuya Yamasoba Ryo Miyake Kazunori Kataoka Makoto Shimazaki Horacio Cabral King Skyfront

Ultra-small nanomedicines which stably deliver oligonucleotides to refractory cancers

Loading video... VIDEO:ย Nanomedicines consisting of one molecule of oligonucleotide and one or two molecules of Y-shaped block copolymer(s), of which the size is approximately 18 nm and is in dynamic equilibrium with free Y-shaped... view moreย  Credit: 2021 Innovation Center of NanoMedicine Summary Ultra-small nanomedicines of approximately 18 nm were fabricated by dynamic ion-pairing between Y-shaped block copolymers and nucleic acid drugs, such as siRNA and antisense drugs. Chemically...
Kanjiro Miyata Mami Satake Kazunori Kataoka Makoto Shimazaki King Skyfront Department Of Material Engineering

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