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Effects of remdesivir in patients hospitalised with COVID-19: a systematic review and individual patient data meta-analysis of randomised controlled trials

This individual patient data meta-analysis showed that remdesivir reduced mortality in patients hospitalised with COVID-19 who required no or conventional oxygen support, but was underpowered to evaluate patients who were ventilated when receiving remdesivir. The effect size of remdesivir in patients with more respiratory support or acquired immunity and the cost-effectiveness of remdesivir remain to be further elucidated.
Nikki Rommers Rosine Mucklow Nina Khanna Lars Hemkens Marco Cattaneo Fabrice Helfenstein

Community Impact Data, 3 New Covid Vaccines, and Trials in Children: A Month of Dilemmas and Good News

Absolutely Maybe Itโ€™s been another drama-filled, and data-packed, hectic few weeks in the Covid vaccines landscape. But the visual theme of this roundup post is the gigantic global airlift thatโ€™s underway at last, and the relief and hope that comes with it. There are the usual updates on the vaccines that have released efficacy results โ€“ and all the phase 3 trials that are underway, with over 460,000 participants so far. Iโ€™ve highlighted major community studies, too, the developments ...
United States United Kingdom South Korea East Timor South Africa City Of
Source: plos.org

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